Build your foundational knowledge of microscopy techniques in nanoscience research
Develop skills in hands-on nanoscience experimentation and scientific communication
Nanoscale Microscopy is a one-week, hands-on, science learning opportunity for high school students on scientific imaging, a topic that is typically only accessible in an advanced college-level course. Specifically, students will be able to explore three essential microscopy techniques for nanoscience research: fluorescence microscopy, scanning probe microscopy, and electron microscopy. This one-week summer course offers an exploratory introduction to this important scientific skill for students as early as 10th grade at the high school level.
For participating students who intend to become science majors in college, this course will provide foundational knowledge of a key element in scientific observation methods. For participating students who might not pursue a science career, the course offers a glimpse into how scientists study the invisible world of atoms and molecules, which enables key technical innovations, from novel drug delivery methods to advanced energy and computational hardware systems.
Nanoscale Microscopy Lab Summer Institute Program
MIMG 15, Nanoscale Microscopy Lab is an exploratory introduction to three key microscopy techniques for nanoscience research: fluorescence microscopy, scanning probe microscopy, and electron microscopy. Nanoscience is an umbrella term that encompasses a diverse, interdisciplinary branch of modern science research, including molecular sciences, biotechnology, material science, chemistry, biochemistry, and various fields of engineering.
Microscopy has been an indispensable tool in the advancement of nanoscience. This course aims to give an overview of the most important modalities of microscopy that are commonly used in nanoscale research. The course will begin with an introduction of the common principles of microscopy and then cover light and confocal microscopy, which itself has had a long and fascinating history. We will then move on to electron microscopy, cryo electron microscopy and tomography, and scanning probe microscopy. The course will include laboratory time for sample preparation techniques and measurements at the instruments. It will also consider few examples highlighting advanced research applications.
Students are required to make a final presentation on a team project.
Application deadline: June 1, 2024 | Enrollment deadline: June 15, 2024
Applications are reviewed and admission to the program is granted on a rolling basis starting February 15th. Applying at your earliest convenience, prior to June 1st, is highly recommended.
The program has application requirements for admission. Eligible applicants who successfully submit all requirements will be reviewed and notified via email of an admission decision within 3 weeks.
Applicants are required to provide the following during the online registration process:
- An unofficial transcript from grade 9 to present reflecting a cumulative GPA of 3.2 or higher
- If your school transcript utilizes a different grading system, please submit your transcript as is. If available, please attach a translation/equivalency guide.
- INTERNATIONAL STUDENTS: If you are an international student, a transcript refers to your complete secondary academic record. To learn more about converting your grades into a US-based GPA, please click here.
- If your school has a translation/equivalency guide, please also include it with your transcript. If you do not have a translation/equivalency guide, please still submit your most up-to-date transcript as is for staff to review.
- Value statement: At the time of registration, ALL applicants will be prompted to submit a few short sentences reflecting on their pursuit of participation in a UCLA Precollege Summer Institute. Please note that students are strongly discouraged from relying on ChatGpt/AI tools for their application responses and are encouraged to submit original and authentic answers.
- Short essay responses to the following prompts:
- A background in basic chemistry and molecular and cellular biology is strongly recommended. List relevant courses or experience you have in the sciences.
- In 250 words or less, please explain how an understanding of microscopy can help you in your future studies or career plan?
- In 150 words or less, please explain what you know about nanoscience or the atomic/molecular scale?
NOTE: Students should compose the essay before beginning the online registration process. There will be text fields on the online registration form of which the response text can be copied.
Due to the intense nature of the Nanoscale Microscopy Lab Summer Institute and the time commitment involved, living in on-campus housing is mandatory.
For more information on UCLA housing precollege programs, please see the Housing for Minors page.
All precollege programs with mandatory housing also feature scheduled non-curricular evening and weekend activities that all students are expected to participate in. The nature of these scheduled activities is at the sole discretion of the individual academic department offering the program, and are not operated by UCLA Summer Sessions. To learn more about when your selected program will host such activities, please consult the schedules for each program, or contact the department in question directly: rita@cnsi.ucla.edu
Most of our precollege programs with mandatory housing will hold check-in on the Sunday before the start of the program between 4-6pm, and hold check-out the Saturday after the final day of class at 11am. Please contact the department in question directly to confirm check-in and check-out times: rita@cnsi.ucla.edu
Coursework
Microbiology, Immunology, and Molecular Genetics (MIMG) 15; 2 units
Grading
Students will be graded on a Pass/No Pass basis upon completion. See University Credit, Grades and Transcripts for more information about academic credit.
In order to successfully complete the program, students are not allowed any excused or unexcused absences.
UCLA Summer Sessions Summer Scholars Support
Qualified students attending grades 9th – 11th in Spring 2024 in the state of California may be eligible for Summer Scholars Support, a need- and merit-based scholarship offered by the UCLA Summer Sessions Office. Students must be 15 years old by the first day of Summer Sessions 2024 on June 24th in order to participate in a Precollege Summer Institute and/or apply for Summer Scholars Support. A limited number of full and partial scholarships are available to support enrollment in SCIP/eSCIP, one Summer Course, or a Precollege Summer Institute.
Summer 2024 deadline to apply: March 15.
Program Dates: June 23 – June 29, 2024
Program Type: In-person
Program Eligibility: 10th-12th grade in Spring 2024*
Application deadline: June 1, 2024
Enrollment deadline: June 15, 2024
*All participants must be at least 15 years of age by the first day of Summer Sessions 2024 on June 24th, no exceptions allowed.
The schedule and syllabus are subject to change. Enrolled students will be given updated materials closer to the program start date.
Fees and Payment Info
The program fee includes the unit fees for the UCLA coursework offered as part of the program and thus varies by UC student status. The program fee also includes the cost of UCLA Housing (for mandatory housing programs). In addition to the program fee, students are assessed other campus and administrative fees during the summer. This is a summary of fees that commonly apply to the selected student type.
Actual tuition and fees are subject to change by the University of California. Visit the fees, payment, and financial aid section for important disclaimer, as well as more details on fees, payment instructions, and information on delinquency, refunds, and financial aid.
Meet Your Instructors
Hong Zhou
FacultyProfessor Hong Zhou is a faculty at the Microbiology, Immunology & Molecular Genetics Department of UCLA. Dr. Zhou is also the Director of the Electron Imaging Center for NanoMachines. Professor Zhou’s lab focuses on 3D structural studies of biological complexes using cryo-electron microscopy (cryoEM) and cryo-electron tomography (cryoET). These emerging methods are particularly suitable for structure determination of large molecular complexes, viruses, cellular machineries and bacterial cells. Recent efforts have focuses on developing and applying advanced cryoEM and cryoET techniques to visualize the dynamic processes of microbial infections and to decipher the mechanisms of fundamental biological processes. Dr. Zhou’s group is at the forefront in pushing the envelope of cryoEM reconstruction to atomic resolution. Dr. Zhou was a Pew Scholar in the Biomedical Sciences, received numerous awards, including the Basil O’Connor Scholar Award, the Established Investigator Award of American Heart Association, the Burton award, and the KH Kuo Award of Distinguished Scientist.
Laurent A. Bentolila
Dr. Laurent A. Bentolila is a biochemist and a molecular geneticist who joined the Department of Chemistry and Biochemistry in 2002. He currently serves as the Scientific Director of both the Advanced Light Microscopy/Spectroscopy Laboratory and the Macro-Scale Imaging Laboratory at CNSI. Dr. Bentolila earned his B.S. in Biochemistry and M.S. in Genetics from Paris-XI University, Orsay and Ph.D. in Molecular Genetics and Immunology from the Pasteur Institute, Paris. He was a European Molecular Biology Organization Postdoctoral fellow at the University of California, Berkeley where he worked on the recombination and expression of antigen receptor genes in lymphocytes. Dr. Bentolila is an elected member of the CNSI Executive Committee and Education Committee. He is actively teaching in Biological Microscopy (MIMG 105) and Introduction to Molecular Imaging (M248). Since becoming Scientific Director of the Advanced Light Microscopy/Spectroscopy Laboratory at CNSI, Dr. Bentolila has developed and assembled a unique collection of custom-made and commercial light microscopy tools for the application of novel spectroscopic methods and advanced microscopy techniques used for the study of macromolecules, cellular dynamics and nano-scale characterization of biomaterials.
Adam Z. Stieg
Dr. Adam Z. Stieg currently serves as the Scientific Director of the Nano and Pico Characterization Core Facility at CNSI as well Director of the Sci|Art NanoLab Institute. Dr. Stieg earned his B.S. with honors in Chemistry from Drew University and both his M.S. and Ph.D. in Inorganic and Physical Chemistry from UCLA. He is a member of the CNSI Executive and Education Committees. As a scientist and educator, Dr. Stieg continues to focus on the development of integrated approaches to study material systems at the interface of traditional boundaries. Through the implementation of original experimental techniques, with a specialized focus in multi-environment, high-performance scanning probe microscopes, his research seeks to bridge the gap between our current understanding of nanomaterials and their fundamental properties with how these systems tend toward complexity at increased scales of space and time. Numerous ongoing, collaborative efforts involve the study of molecular machines, nanoparticles for targeted drug delivery, inorganic carbon-based materials, directed stem cell differentiation and the pursuit of physically intelligent systems through neuromorphic computation. His research activities are augmented by active collaboration with artists and designers on various projects, installations, and public exhibitions that directly inform the scientific process and provide motivation to develop new educational content that conveys the need for creativity in innovation.
Nanoscale Microscopy Lab Summer Institute FAQ
Nanoscale microscopy is the practice of using microscopes and different techniques to study nanoscale objects.
Most work will be done in class but students will have some assignments outside of class.
We expect students to have a strong background in chemistry and biology (honors/AP chemistry experience preferred).
Yes, students should bring laptops.
Still have questions? Check out the general Summer Institutes FAQ.